文EON体育4注册學術報告—Modeling and research on an immuno-epidemiological coupled system with coinfection

發布者:系統管理員發布時間:2022-04-10瀏覽次數🥹:77

題目:Modeling and research on an immuno-epidemiological coupled system with coinfection

時間🚇:2022年4月12日🦘,19:00-20:30

地點:騰訊會議(會議號🙂‍↕️:685-217-898

主講人: 李學誌教授(河南財政金融EON4、河南師範大學)

摘要🩲👩🏼‍🚒:In this talk, a two-strain model with coinfection that links immunological and epidemiological dynamics across scales is formulated. On the with-in host scale, the two strains eliminate each other with the strain having the larger immunological reproduction number persisting. However, on the population scale coinfection is a common occurrence. Individuals infected with strain one can become coinfected with strain two, and similarly for individuals originally infected with strain two. The immunological reproduction numbers Rj , the epidemiological reproduction numbers Rj and invasion reproduction numbers Rij are computed. Besides the disease-free equilibrium, there are strain one and strain two dominance equilibria. The disease-free equilibrium is locally asymptotically stable when the epidemiological reproduction numbers Rj are smaller than one. In addition, each strain dominance equilibrium is locally asymptotically stable if the corresponding epidemiological reproduction number is larger than one and the invasion reproduction number of the other strain is smaller than one. The coexistence equilibrium exists when all the reproduction numbers are greater than one. Simulations suggest that when both invasion reproduction numbers are smaller than one bistability occurs with one of the strains persisting or the other, depending on initial conditions.

主講人簡介:博士🍍,二級教授👨🏼‍⚕️🦉,博士生導師,河南省優秀專家,河南省基礎研究領軍人才🕵🏼‍♂️,教育部數學類專業教學指導委員會委員,中國數學會生物數學專業委員會副理事長。主要研究領域:應用泛函分析💌,生物數學⛳️,傳染病動力學。主持國家自然科學基金面上項目5項🥘,在德國Springer出版社出版學術著作2部,在國內出版學術著作或教材5部,在國外和國內核心期刊發表學術論文160余篇,其中被SCI收錄100余篇,20次應邀到美國、意大利、英國💃🏿、加拿大、日本、韓國👨🏿‍✈️、印度等國訪問🎓、講學💱🤾🏼‍♀️、參加國際學術會議💅。

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